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Sample size calculators

Pick by design: every calculation runs in the deterministic server-side solver, validated against G*Power and R pwr. Free; no sign-up.

Comparing means

Two-sample t-test sample size calculatorComparing the means of two independent groups: participants per arm from Cohen's d, α and power.Paired t-test sample size calculatorBefore–after in the same person, or two methods on the same subjects: complete records from dz.One-way ANOVA sample size calculatorThree or more independent groups: total sample from Cohen's f and the number of groups.Mann-Whitney U test sample size calculatorSkewed outcome or small sample: n for the non-parametric two-group comparison.Non-inferiority sample size calculator (means)Showing the new method is not meaningfully worse: per-arm n from the margin and the SD.

Comparing rates

Sample size calculator for comparing two proportionsComparing complication, success or response rates between two groups: per-arm n from p₁ and p₂.

Diagnostic accuracy

Sensitivity / specificity sample size calculatorEstimating a diagnostic test's accuracy with a confidence interval: diseased cases from the expected value and CI half-width.Sample size: sensitivity above a thresholdShowing a test's sensitivity exceeds a clinical threshold: cases from the expected value and the threshold.McNemar sample size calculator (paired tests)Comparing two diagnostic tests on the same patients: cases from the discordant-pair rates.

Scenario comparison, cluster designs and the literature-searching Measurer live in the full tool. For the concepts, see the effect size and sample size adjustments guides.